2025 Audi S4 vs 2025 Mercedes-Benz E-Class
Comparison Overview
The most significant numerical disparity between the 2025 Audi S4 and the 2025 Mercedes-Benz E-Class is the $7,550 MSRP gap, with the S4 priced at $54,900 versus the E-Class's $62,450. Performance figures heavily favor the S4, delivering 349 hp and 369 lb-ft of torque compared to the E-Class's 255 hp and 295 lb-ft of torque. Conversely, the E-Class shows superior efficiency, achieving a combined 28 MPG versus the S4's 24 MPG, leading to a 4 MPG difference. Dimensionally, the E-Class is longer at 194.9 inches against the S4's 187.5 inches, contributing to its marginally larger 12.7 cu ft cargo area compared to the S4's 12.0 cu ft. The S4 utilizes AWD while the E-Class is RWD, creating distinct driving dynamics for different users.
Size Comparison
Performance
Fuel Efficiency
Full Specifications
Our Verdicts
2025 Mercedes-Benz E-Class
The 2025 Mercedes-Benz E-Class offers superior fuel economy at 28 combined MPG, resulting in lower operational costs for daily driving.
2025 Mercedes-Benz E-Class
The E-Class provides slightly more utility with a marginally larger 12.7 cu ft of cargo capacity and greater overall exterior dimensions.
2025 Audi S4
The 2025 Audi S4 clearly dominates in output with 349 hp and 369 lb-ft of torque, substantially exceeding the E-Class's output.
2025 Audi S4
The Audi S4 offers significantly more performance horsepower for $7,550 less than the entry-level Mercedes-Benz E-Class.
Choose the Audi S4 if...
- You prioritize acceleration and raw power, as the S4 produces 349 hp.
- You are looking for the lowest entry price point at $54,900.
- You prefer the traction advantage provided by its standard All-Wheel Drive system.
Choose the Mercedes-Benz E-Class if...
- Fuel savings are critical, evidenced by its 28 combined MPG rating.
- You require a longer wheelbase, as the E-Class measures 194.9 inches long.
- You prefer the traditional handling characteristics associated with its Rear Wheel Drive layout.
Key Dimensions
| Dimension | Audi S4 | Mercedes-Benz E-Class |
|---|---|---|
| Length | 187.5" | 194.9" |
| Width | 72.7" | 74.0" |
| Height | 56.2" | 57.9" |
| Wheelbase | 111.0" | 116.6" |
Features Comparison
Safety
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Lane Departure Warning | ✓ | — |
| Lane Keeping Assist System | ✓ | — |
| Pre-Collision Safety System | ✓ | ✓ |
| Post-Collision Safety System | ✓ | ✓ |
| Dual Front Side-Mounted Airbags | ✓ | ✓ |
| Front Head Airbags | ✓ | ✓ |
| Rear Head Airbags | ✓ | ✓ |
| Passenger Airbag Occupant Sensing Deactivation | ✓ | ✓ |
| Electronic Stability Control | ✓ | ✓ |
| Traction Control System | ✓ | ✓ |
| LATCH System | ✓ | ✓ |
| Rear Door Child Safety Locks | ✓ | ✓ |
| Anti-lock Brakes (ABS) | 4-Wheel | 4-Wheel |
| Front Ventilated Disc Brakes | ✓ | ✓ |
| Rear Ventilated Disc Brakes | ✓ | ✓ |
| Brake Preparation System | ✓ | ✓ |
| Brake Assist | ✓ | ✓ |
| Tire Pressure Monitoring System | ✓ | ✓ |
| Automatic Headlights | ✓ | ✓ |
| Headlight Delay-Off | ✓ | ✓ |
| LED Headlights | ✓ | ✓ |
| Self-Leveling Headlights | ✓ | — |
| Daytime Running Lights | ✓ | ✓ |
| Integrated Turn Signal Mirrors | ✓ | ✓ |
| Front Headrests | 2 | 2 |
| Front Integrated Headrests | ✓ | — |
| Rear Headrests | 3 | 3 |
| Rear Height Adjustable Headrests | ✓ | ✓ |
| Rear Center 3-Point Seatbelt | ✓ | ✓ |
| Engine Immobilizer | ✓ | ✓ |
| Blind Spot Monitor | — | ✓ |
| Driver Attention Alert | — | ✓ |
| Brake Drying | — | ✓ |
| Adaptive Headlights | — | ✓ |
| Front Power Adjustable Headrests | — | ✓ |
| Anti-Theft Alarm System (Remote) | — | ✓ |
Engine
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Base Engine Displacement | 3.0 L | 2.0 L |
| Number of Cylinders | V6 | inline 4 |
| Base Engine Type | gas | mild hybrid |
| Horsepower | 349 hp @ 6300 rpm | 255 hp @ 5800 rpm |
| Torque | 369 lb-ft @ 3200 rpm | 295 lb-ft @ 2000 rpm |
| Number of Valves | 24 | 16 |
| Camshaft Type | Double overhead cam (DOHC) | Double overhead cam (DOHC) |
| Variable Valve Timing | Variable | Variable |
| Fuel Injection Type | ✓ | ✓ |
Drive Train
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Transmission Type | 8-speed shiftable automatic | 9-speed shiftable automatic |
| Drivetrain Type | all wheel drive | rear wheel drive |
| Center Differential Type | Limited Slip | — |
Fuel
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Fuel Type | premium unleaded (recommended) | premium unleaded (required) |
| EPA Fuel Economy (City/Highway) | 20/29 MPG | 25/33 MPG |
| EPA Fuel Economy (Combined) | 24 MPG | 28 MPG |
| EPA Driving Range (City/Highway) | 306.0/443.7 mi. | 435.0/574.2 mi. |
| Fuel Tank Capacity | 15.3 gal. | 17.4 gal. |
Comfort & Convenience
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Push Button Start | ✓ | ✓ |
| Tilt and Telescopic Steering Wheel | ✓ | — |
| Transmission Controls on Steering Wheel | ✓ | ✓ |
| Audio Controls on Steering Wheel | ✓ | ✓ |
| Electric Power Steering | ✓ | ✓ |
| Rear View Camera | ✓ | ✓ |
| Front Parking Sensors | ✓ | ✓ |
| Rear Parking Sensors | ✓ | ✓ |
| Adaptive Cruise Control | ✓ | — |
| Universal Remote Transmitter | ✓ | ✓ |
| Front Cupholders | ✓ | ✓ |
| Rear Cupholders | ✓ | ✓ |
| Front Door Pockets | ✓ | ✓ |
| Rear Door Pockets | ✓ | ✓ |
| Front Seatback Storage | ✓ | ✓ |
| Leather Steering Wheel | ✓ | ✓ |
| Heated Steering Wheel | ✓ | — |
| Three Zone Climate Control | ✓ | — |
| Rear Ventilation Ducts with Fan Control | ✓ | — |
| Dual Vanity Mirrors | ✓ | ✓ |
| Auto-Dimming Rearview Mirror | ✓ | ✓ |
| Turn Signal Indicators in Mirrors | ✓ | ✓ |
| Power Tilt and Telescopic Steering Wheel | — | ✓ |
| Cruise Control on Steering Wheel | — | ✓ |
| Front View Camera | — | ✓ |
| Side View Camera | — | ✓ |
| Automatic Parking Assist | — | ✓ |
| Wireless Charging Pad | — | ✓ |
| Cruise Control | — | ✓ |
| Overhead Console with Storage | — | ✓ |
| Dual Zone Climate Control | — | ✓ |
| Rear Ventilation Ducts | — | ✓ |
| Interior Air Filtration | — | ✓ |
In Car Entertainment
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Infotainment Display | 10.1 in | 14.4 in |
| AM/FM Stereo | ✓ | ✓ |
| Stereo Power | 180W | — |
| Speaker System | 10 | 6 |
| Subwoofer Count | 1 | — |
| Apple CarPlay (Wireless) | ✓ | ✓ |
| Android Auto (Wired) | ✓ | — |
| USB Port | ✓ | ✓ |
| USB Port with External Media Control | ✓ | ✓ |
| Android Auto (Wireless) | — | ✓ |
| Satellite Radio | — | ✓ |
| Satellite Radio Trial Period | — | 6 months |
Power Feature
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| One-Touch Power Windows | 4 | 4 |
| Moonroof Type | 1st Row Power Glass | 1st Row Power Glass Extended |
| Remote Keyless Entry | ✓ | — |
| Heated Mirrors | ✓ | ✓ |
| Keyless Entry | — | ✓ |
Frontseats
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Front Head Room | 37.3 in. | 37.3 in. |
| Front Leg Room | 41.3 in. | 41.5 in. |
| Front Shoulder Room | 55.9 in. | 57.8 in. |
| Seat Material: Leather/Sueded Microfiber | ✓ | — |
| Front Seat Type: Sport | ✓ | — |
| Driver Seat Power Adjustments | 8-way | 10-way |
| Driver Seat Height Adjustment | ✓ | ✓ |
| Driver Seat Lumbar Support | Power | Power |
| Passenger Seat Power Adjustments | 8-way | 10-way |
| Passenger Seat Height Adjustment | ✓ | ✓ |
| Passenger Seat Lumbar Support | Power | Power |
| Driver Seat Heating | Multi-level | Multi-level |
| Passenger Seat Heating | Multi-level | Multi-level |
| Seat Massage Function | ✓ | — |
| Seat Material: Leatherette | — | ✓ |
| Front Seat Type: Bucket | — | ✓ |
| Driver Seat Thigh Extension | — | ✓ |
| Driver Seat Memory Settings | — | 3 |
| Passenger Seat Thigh Extension | — | ✓ |
| Passenger Seat Memory Settings | — | 3 |
Rearseats
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Rear Head Room | 37.4 in. | 37.6 in. |
| Rear Leg Room | 35.7 in. | 36.2 in. |
| Rear Shoulder Room | 54.5 in. | 57.1 in. |
| Split-Folding Rear Seatback | ✓ | ✓ |
| Folding Rear Seat Feature | ✓ | — |
| Pass-Thru Center Armrest | ✓ | — |
| Folding Center Armrest | — | ✓ |
Tires and Wheels
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Wheel Material | Alloy | — |
| Wheel Diameter | 19 in | — |
| Tire Type | Performance | — |
| Tire Size | ✓ | 225/55R18 |
| Spare Tire Type | Temporary | — |
| Spare Tire Location | Inside Mounted | — |
| Wheel Finish | — | Painted Alloy |
| Wheel Size | — | 18 x 8.0 in |
| Run Flat Tires | — | ✓ |
Suspension
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Four-Wheel Independent Suspension | ✓ | ✓ |
| Front Stabilizer Bar | ✓ | ✓ |
| Rear Stabilizer Bar | ✓ | ✓ |
Warranty
| Feature | Audi | Mercedes-Benz |
|---|---|---|
| Basic Warranty | — | 4 yr./ 50000 mi. |
| Drivetrain Warranty | — | 4 yr./ 50000 mi. |
| Hybrid Component Warranty | — | 6 yr./ 62000 mi. |
| Corrosion/Rust Warranty | — | 4 yr./ 50000 mi. |
| Roadside Assistance | — | 4 yr./ 50000 mi. |
Frequently Asked Questions
Common questions about comparing the 2025 Audi S4 and 2025 Mercedes-Benz E-Class.
What is the power difference between these two sedans?
The 2025 Audi S4 has a distinct performance advantage, generating 349 horsepower and 369 lb-ft of torque. In contrast, the 2025 Mercedes-Benz E-Class produces 255 horsepower and 295 lb-ft of torque.
How much more expensive is the Mercedes-Benz E-Class?
The E-Class commands a $7,550 premium over the S4; its MSRP starts at $62,450, while the S4 begins at $54,900. Both vehicles require premium unleaded fuel, though the E-Class mandates it.
Which car is more practical for long highway commutes?
The E-Class is better suited for high-mileage commuters, achieving 28 combined MPG compared to the S4's 24 combined MPG. The E-Class also offers slightly better Highway MPG at 33 MPG versus the S4's 29 MPG.
What are the major mechanical differences in their drivetrains?
The Audi S4 comes standard with an 8-speed automatic transmission paired with All-Wheel Drive. The Mercedes-Benz E-Class utilizes a 9-speed automatic transmission but employs a Rear Wheel Drive layout.
Are the physical sizes of the cars significantly different?
Yes, the E-Class is noticeably larger overall, measuring 194.9 inches in length compared to the S4's 187.5 inches. This results in the E-Class offering a slightly larger cargo volume of 12.7 cu ft versus the S4's 12.0 cu ft.
Do the horsepower figures translate directly to better enthusiast driving?
While the S4 has 94 more horsepower, the E-Class's longer body and lower power rating suggest it will have a smoother, potentially more composed ride rather than raw acceleration focus.
More Premium Sedans ($50k-$80k)
View allVehicle Details
Compare More Vehicles
Use our interactive comparison tool to compare up to 4 vehicles at once
Open Comparison Tool