2025 Audi S4 vs 2026 Mercedes-Benz E-Class

Audi S4

$54,900 · Sedan

vs
Mercedes-Benz E-Class

$63,900 · Sedan

Comparison Overview

The 2025 Audi S4 unleashes immediate thrill with 349 hp and 369 lb-ft of torque, showcasing Germanic performance prowess in a compact shell. In contrast, the 2026 Mercedes-Benz E-Class leans into refined luxury, offering a more substantial presence at 194.9 inches long. The performance gap is significant: the S4 boasts 94 more horsepower than the E-Class’s 255 hp, translating to superior acceleration for the Audi. Conversely, the Mercedes counters with superior efficiency, achieving 28 combined MPG versus the S4’s 24 combined MPG. The pricing dynamic is also stark, with the E-Class commanding a $63,900 MSRP compared to the S4’s $54,900 entry point. While both offer all-weather assurance via AWD (Audi) or RWD sophistication (Mercedes), the S4 delivers visceral power for $9,000 less, making it the choice for raw excitement.

Size Comparison

Performance

Fuel Efficiency

Full Specifications

Our Verdicts

🚗 Best for Commuters

2026 Mercedes-Benz E-Class

The 2026 Mercedes-Benz E-Class wins for commuters due to its better 28 combined MPG rating, offering less frequent stops at the pump.

👨‍👩‍👧‍👦 Best for Families

2026 Mercedes-Benz E-Class

The longer and slightly wider 2026 Mercedes-Benz E-Class offers marginally more interior space and cargo volume at 12.7 cu ft.

🏎️ Best for Enthusiasts

2025 Audi S4

The 2025 Audi S4 is the clear choice for driving enthusiasts, packing 349 hp compared to the E-Class’s 255 hp.

💰 Best Value

2025 Audi S4

The 2025 Audi S4 provides substantially more performance for $9,000 less than the equivalent Mercedes-Benz E-Class.

Choose the Audi S4 if...

  • You prioritize exhilarating performance, leveraging the S4's superior 349 horsepower output.
  • You are budget-conscious and prefer to save $9,000 off the base MSRP.
  • You value the assured grip of an All-Wheel Drive system in a performance package.

Choose the Mercedes-Benz E-Class if...

  • Fuel economy is paramount, as the E-Class achieves 33 MPG highway versus the S4's 29 MPG highway.
  • You desire the sophisticated stability of a Rear Wheel Drive platform.
  • You prefer a longer vehicle footprint, as the E-Class measures 194.9 inches long.

Key Dimensions

Dimension Audi S4 Mercedes-Benz E-Class
Length 187.5" 194.9"
Width 72.7" 74.0"
Height 56.2" 57.9"
Wheelbase 111.0" 116.6"

Features Comparison

Safety
Feature Audi Mercedes-Benz
Lane Departure Warning ✓ —
Lane Keeping Assist System ✓ —
Pre-Collision Safety System ✓ ✓
Post-Collision Safety System ✓ ✓
Dual Front Side-Mounted Airbags ✓ ✓
Front Head Airbags ✓ ✓
Rear Head Airbags ✓ ✓
Passenger Airbag Occupant Sensing Deactivation ✓ ✓
Electronic Stability Control ✓ ✓
Traction Control System ✓ ✓
LATCH System ✓ ✓
Rear Door Child Safety Locks ✓ ✓
Anti-lock Brakes (ABS) 4-Wheel 4-Wheel
Front Ventilated Disc Brakes ✓ ✓
Rear Ventilated Disc Brakes ✓ ✓
Brake Preparation System ✓ ✓
Brake Assist ✓ ✓
Tire Pressure Monitoring System ✓ ✓
Automatic Headlights ✓ ✓
Headlight Delay-Off ✓ ✓
LED Headlights ✓ ✓
Self-Leveling Headlights ✓ —
Daytime Running Lights ✓ ✓
Integrated Turn Signal Mirrors ✓ ✓
Front Headrests 2 2
Front Integrated Headrests ✓ —
Rear Headrests 3 3
Rear Height Adjustable Headrests ✓ ✓
Rear Center 3-Point Seatbelt ✓ ✓
Engine Immobilizer ✓ ✓
Blind Spot Monitor — ✓
Driver Attention Alert — ✓
Brake Drying — ✓
Adaptive Headlights — ✓
Front Power Adjustable Headrests — ✓
Anti-Theft Alarm System (Remote) — ✓
Engine
Feature Audi Mercedes-Benz
Base Engine Displacement 3.0 L 2.0 L
Number of Cylinders V6 inline 4
Base Engine Type gas mild hybrid
Horsepower 349 hp @ 6300 rpm 255 hp @ 5800 rpm
Torque 369 lb-ft @ 3200 rpm 295 lb-ft @ 2000 rpm
Number of Valves 24 16
Camshaft Type Double overhead cam (DOHC) Double overhead cam (DOHC)
Variable Valve Timing Variable Variable
Fuel Injection Type ✓ ✓
Drive Train
Feature Audi Mercedes-Benz
Transmission Type 8-speed shiftable automatic 9-speed shiftable automatic
Drivetrain Type all wheel drive rear wheel drive
Center Differential Type Limited Slip —
Fuel
Feature Audi Mercedes-Benz
Fuel Type premium unleaded (recommended) premium unleaded (required)
EPA Fuel Economy (City/Highway) 20/29 MPG 25/33 MPG
EPA Fuel Economy (Combined) 24 MPG 28 MPG
EPA Driving Range (City/Highway) 306.0/443.7 mi. 435.0/574.2 mi.
Fuel Tank Capacity 15.3 gal. 17.4 gal.
Comfort & Convenience
Feature Audi Mercedes-Benz
Push Button Start ✓ ✓
Tilt and Telescopic Steering Wheel ✓ —
Transmission Controls on Steering Wheel ✓ ✓
Audio Controls on Steering Wheel ✓ ✓
Electric Power Steering ✓ ✓
Rear View Camera ✓ ✓
Front Parking Sensors ✓ ✓
Rear Parking Sensors ✓ ✓
Adaptive Cruise Control ✓ —
Universal Remote Transmitter ✓ ✓
Front Cupholders ✓ ✓
Rear Cupholders ✓ ✓
Front Door Pockets ✓ ✓
Rear Door Pockets ✓ ✓
Front Seatback Storage ✓ ✓
Leather Steering Wheel ✓ ✓
Heated Steering Wheel ✓ —
Three Zone Climate Control ✓ —
Rear Ventilation Ducts with Fan Control ✓ —
Dual Vanity Mirrors ✓ ✓
Auto-Dimming Rearview Mirror ✓ ✓
Turn Signal Indicators in Mirrors ✓ ✓
Power Tilt and Telescopic Steering Wheel — ✓
Cruise Control on Steering Wheel — ✓
Front View Camera — ✓
Side View Camera — ✓
Automatic Parking Assist — ✓
Wireless Charging Pad — ✓
Cruise Control — ✓
Overhead Console with Storage — ✓
Dual Zone Climate Control — ✓
Rear Ventilation Ducts — ✓
Interior Air Filtration — ✓
In Car Entertainment
Feature Audi Mercedes-Benz
Infotainment Display 10.1 in 14.4 in
AM/FM Stereo ✓ ✓
Stereo Power 180W —
Speaker System 10 6
Subwoofer Count 1 —
Apple CarPlay (Wireless) ✓ ✓
Android Auto (Wired) ✓ —
USB Port ✓ ✓
USB Port with External Media Control ✓ ✓
Android Auto (Wireless) — ✓
Satellite Radio — ✓
Satellite Radio Trial Period — 6 months
Power Feature
Feature Audi Mercedes-Benz
One-Touch Power Windows 4 4
Moonroof Type 1st Row Power Glass 1st Row Power Glass Extended
Remote Keyless Entry ✓ —
Heated Mirrors ✓ ✓
Keyless Entry — ✓
Frontseats
Feature Audi Mercedes-Benz
Front Head Room 37.3 in. 37.3 in.
Front Leg Room 41.3 in. 41.5 in.
Front Shoulder Room 55.9 in. 57.8 in.
Seat Material: Leather/Sueded Microfiber ✓ —
Front Seat Type: Sport ✓ —
Driver Seat Power Adjustments 8-way 10-way
Driver Seat Height Adjustment ✓ ✓
Driver Seat Lumbar Support Power Power
Passenger Seat Power Adjustments 8-way 10-way
Passenger Seat Height Adjustment ✓ ✓
Passenger Seat Lumbar Support Power Power
Driver Seat Heating Multi-level Multi-level
Passenger Seat Heating Multi-level Multi-level
Seat Massage Function ✓ —
Seat Material: Leatherette — ✓
Front Seat Type: Bucket — ✓
Driver Seat Thigh Extension — ✓
Driver Seat Memory Settings — 3
Passenger Seat Thigh Extension — ✓
Passenger Seat Memory Settings — 3
Rearseats
Feature Audi Mercedes-Benz
Rear Head Room 37.4 in. 37.6 in.
Rear Leg Room 35.7 in. 36.2 in.
Rear Shoulder Room 54.5 in. 57.1 in.
Split-Folding Rear Seatback ✓ ✓
Folding Rear Seat Feature ✓ —
Pass-Thru Center Armrest ✓ —
Folding Center Armrest — ✓
Tires and Wheels
Feature Audi Mercedes-Benz
Wheel Material Alloy —
Wheel Diameter 19 in —
Tire Type Performance —
Tire Size ✓ 225/55R18
Spare Tire Type Temporary —
Spare Tire Location Inside Mounted —
Wheel Finish — Painted Alloy
Wheel Size — 18 x 8.0 in
Run Flat Tires — ✓
Suspension
Feature Audi Mercedes-Benz
Four-Wheel Independent Suspension ✓ ✓
Front Stabilizer Bar ✓ ✓
Rear Stabilizer Bar ✓ ✓
Warranty
Feature Audi Mercedes-Benz
Basic Warranty — 4 yr./ 50000 mi.
Drivetrain Warranty — 4 yr./ 50000 mi.
Hybrid Component Warranty — 6 yr./ 62000 mi.
Corrosion/Rust Warranty — 4 yr./ 50000 mi.
Roadside Assistance — 4 yr./ 50000 mi.

Frequently Asked Questions

Common questions about comparing the 2025 Audi S4 and 2026 Mercedes-Benz E-Class.

How does the power difference impact daily driving between the 2025 Audi S4 and the 2026 Mercedes-Benz E-Class?

The Audi S4 is significantly more potent, generating 349 hp and 369 lb-ft of torque, which translates to immediate responsiveness and quicker passing ability. The E-Class, with 255 hp, offers a much smoother, less aggressive power delivery focused more on refined cruising.

Is the Audi S4’s AWD superior to the E-Class’s RWD for year-round use?

The S4's All-Wheel Drive system is inherently better for maximum traction in adverse conditions like snow or heavy rain. The E-Class utilizes a traditional Rear Wheel Drive layout, which typically provides a better feel for steering dynamics but requires more caution in slippery situations.

Considering the cost, is the 2026 Mercedes-Benz E-Class worth the extra $9,000 over the Audi S4?

The $9,000 price difference means the E-Class buyer is paying a premium, likely for advanced standard luxury features not detailed here, alongside better fuel economy. However, for performance-per-dollar, the Audi S4 offers substantially more horsepower for the lower investment.

How much better is the fuel economy for the Mercedes-Benz E-Class?

The E-Class offers a notable efficiency advantage, achieving 28 combined MPG versus the S4’s 24 combined MPG. This gap widens on the highway where the E-Class hits 33 MPG while the S4 achieves 29 MPG.

Which sedan is physically larger, the 2025 Audi S4 or the 2026 Mercedes-Benz E-Class?

The 2026 Mercedes-Benz E-Class is the physically larger vehicle across the board; it is 194.9 inches long compared to the S4’s 187.5 inches. The E-Class is also wider (74.0 inches vs 72.7 inches) and slightly taller.

Do both sedans require premium fuel?

Yes, both vehicles require premium fuel for optimal performance, though the Audi S4 labels it as 'recommended' while the 2026 Mercedes-Benz E-Class mandates it, signaling stricter tuning requirements.

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